Organ-specific models-MetaMouse®
GFP models-OncoBrite®
Angiogenesis models-AngioMouse®
Bone metastases

Liver cancer models
Features
  • Orthotopic transplantation of intact tissue
  • Metastatic sites
    • lymph nodes
    • liver
    • lung
    • peritoneum
  • Green Fluorescent Protein expression

1.   Sun, F.X., Tang, Z.Y., Liu, K.D., Ye, S.L., Xue, Q., Gao, D.M., and Ma, Z.C. Establishment of a metastatic model of human hepatocellular carcinoma in nude mice via orthotopic implantation of histologically intact tissues. Int. J. Cancer 66, 239-243, 1996.

2. Sun, F-X., Tang, Z-Y., Liu, K-D., Xue, Q., Gao, D-M., Yu, Y-Q., Zhou, X-D., Ma, Z-C. Metastatic models of human liver cancer in nude mice orthotopically constructed by using histologically intact patient specimens. J. Cancer Res. Clin. Oncol. 122, 397-402, 1996.

3. Rashidi, B., An, Z., Sun, F-X, Li, X-M., Tang, Z.Y., Moossa, A.R., and Hoffman, R.M. Efficacy of intra-hepatectomy 5-FU on recurrence and metastasis of human hepatocellular carcinoma in nude mice. Int. J. Cancer 91, 231-235, 2001.

4. Wu, M., Mazarchuk, R., Chaudhary, N.D., Spernyak, J., Veith, J., Pera, P., Greco, W., Hoffman, R.M., Kobayashi, T., and Bernacki, R.J. High Resolution Magnetic Resonance Imaging of the Efficacy of the Cytosine Analogue 1-[2-C-Cyano-2-deoxy-b-D-arabino-pentofuranosyl]-N4 - palmitoyl Cytosine (CS-682) in a Liver-Metastasis Athymic Nude Mouse Model. Cancer Res. 63, 2477-2482, 2003. 

ORGAN SPECIFIC MODELS

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