Example: Human LOX-1-GFP
melanoma metastasized to lung (A), lymp node (B), bone
(C) and adrenal gland (D) of nude mouse.
Features
Orthotopic transplantation of intact tissue
Metastatic sites
lymph nodes
lung
skeleton
brain
kidney
adrenal glands
Green Fluorescent
Protein expression
1. Yang, M., Jiang, P., An, Z., Baranov, E., Li, L., Hasegawa, S.,
Al-Tuwaijri, M., Chishima, T., Shimada, H., Moossa, A.R., Hoffman, R.M.
Genetically fluorescent melanoma bone and organ metastasis models.
Clinical Cancer Res. 5, 3549-3559, 1999.
