lymph nodes liver diaphragm adrenal glands stomach duodenum peritoneum lung kidney spleen omentum
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Example
BxPC-3-GFP pancreatic carcinoma growing on pancreas with liver and spleen metastasis. Whole-body image. White arrows - primary tumor, red arrow - spleen metastasis, yellow arrow - liver metastasis. |
1. Fu, X., Guadagni, F., and Hoffman, R.M. A metastatic nude-mouse model of human pancreatic cancer constructed orthotopically from histologically intact patient specimens. Proc. Natl. Acad. Sci. USA 89, 5645-5649, 1992.
2. Furukawa, T., Kubota, T., Watanabe, M., Kitajima, M., and Hoffman, R.M. A novel "patient-like" treatment model of human pancreatic cancer constructed using orthotopic transplantation of histologically intact human tumor tissue in nude mice. Cancer Res. 53, 3070-3072, 1993.
3. An, Z., Wang, X., Kubota, T., Moossa, A.R., Hoffman, R.M. A clinical nude mouse metastatic model for highly malignant human pancreatic cancer. Anticancer Res. 16, 627-632, 1996.
4. Tomikawa, M., Kubota, T., Matsuzaki, S.W., Takahasi, S., Kitajima, M., Moossa, A.R., and Hoffman, R.M. Mitomycin C and cisplatin increase survival in a human pancreatic cancer metastatic model. Anticancer Res. 17, 3623-3626, 1997.
5. Bouvet, M., Yang, M., Nardin, S., Wang, X., Jiang, P., Baranov, E., Moossa, A.R., Hoffman, R.M. Chronologically-specific metastatic targeting of human pancreatic tumors in orthotopic models. Clinical & Experimental Metastasis 18, 213-218, 2000.
6. Lee, N.C., Bouvet, M., Nardin, S., Jiang, P., Baranov, E., Rashidi, B., Yang, M., Wang, X., Moossa, A.R., and Hoffman, R.M. Antimetastatic efficacy of adjuvant gemcitabine in a pancreatic cancer orthotopic model. Clinical & Experimental Metastasis 18, 379-384, 2001.
7. Bouvet, M., Wang, J-W., Nardin, S.R., Nassirpour, R., Yang, M., Baranov, E., Jiang, P., Moossa, A.R., and Hoffman, R.M. Real-time optical imaging of primary tumor growth and multiple metastatic events in a pancreatic cancer orthotopic model. Cancer Research, in press.
8. Bouvet, M., Nardin, S.R., Burton, D.W., Lee, N.C., Yang M., Wang, X., Baranov, E., Behling, C., Moosa, A.R., Hoffman R.M., and Deftos L.J. Parathyroid hormone-related protein as a novel tumor marker in pancreatic adenocarcinoma. Pancreas 24, 284-290, 2002.
