Stomach cancer models
lymph nodes liver lung pancreas adrenal gland kidney peritoneum
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Example
NUGC-4-GFP human stomach tumor in nude mouse. Primary tumor- red arrow, lymph node metastases - white arrows
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1. Furukawa, T., Fu, X., Kubota, T., Watanabe, M., Kitajima, M., and Hoffman, R.M. Nude mouse metastatic models of human stomach cancer constructed using orthotopic implantation of histologically intact tissue. Cancer Res. 53, 1204-1208, 1993.
2. Furukawa, T., Kubota, T., Watanabe, M., Kitajima, M., and Hoffman, R.M. Orthotopic transplantation of histologically intact clinical specimens of stomach cancer to nude mice: Correlation of metastatic sites in mouse and individual patient donors. Int. J. Cancer 53, 608-612, 1993.
3. Furukawa, T., Kubota, T., Watanabe, M., Kitajima, M., and Hoffman, R.M. Differential chemosensitivity of local and metastatic human gastric cancer after orthotopic transplantation of histologically intact tumor tissue in nude mice. Int. J. Cancer 54, 397-401, 1993.
4. Inada, T., Ichikawa, A., Kubota, T., Ogata, Y., Moossa, A.R., and Hoffman, R.M. 5-FU-induced apoptosis correlates with efficacy against human gastric and colon cancer xenografts in nude mice. Anticancer Res. 17, 1965-1972, 1997.
5. Hasegawa, S., Yang, M., Chishima, T., Shimada, H., Moossa, A.R., Hoffman, R.M. In vivo tumor delivery of the green fluorescent protein gene to report future occurrence of metastasis. Cancer Gene Therapy 7, 1336-1340, 2000.